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  1. Aida Suárez-Barrientos1,
  2. Borja Ibanez1,2
  1. 1Coronary Care Unit, Cardiovascular Institute, Hospital Clínico San Carlos, Madrid, Spain
  2. 2Atherothrombosis and Imaging Department, Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Madrid, Spain
  1. Correspondence to Dr Borja Ibanez, Imaging in Experimental Cardiology Laboratory, Atherothrombosis and Imaging Department, Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), c/Melchor Fernández Almagro, 3, Madrid 28029, Spain; bibanez{at}cnic.es

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The Authors' reply We appreciate the letter from Domínguez-Rodriguez and Abreu-Gonzalez1 regarding our recent paper on circadian variations of infarct size.2 They claim that the potential role of melatonin in the association between circadian variations and cardiovascular events should be highlighted.

The circadian clock is regulated by the suprachiasmatic nucleus. Among other effects, it controls melatonin …

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