Objective To assess the effect of delayed percutaneous coronary intervention (PCI) on left ventricle remodeling after acute myocardial infarction (AMI).
Methods Ninety six patients with ST-segment elevation acute interior wall myocardial infarction (AAMI) and with the total occluded left anterior descending coronary artery conformed by angiography at 10.2±2.5 (7∼14) days after onset were divided into two groups according to stent implantation: PCI group and control group. To detect the left ventricular function (LVEF), left ventricular end-diastolic volume index (LVEDVI), left ventricular end-systolic volume index (LVESVI) and left ventricular wall motion abnormality (VWMA), two dimensional echocardiogram was performed before operation (9.0±2.5 days after AMI) and at 2 and 6 months after onset of AAMI respectively.
Results LVEF, LVEDVI, LVESVI and VWMA score were similar in two groups before operation and 2 months after the onset of AAMI, LVEF and VWMA scores did not changed significantly at 6 months in each group compared with those before operation and at 2 months (p>0.05). But LVEDVI and LVESVI were improved significantly in the successful PCI group than those before operation and in the control group (p<0.01, p<0.05).
Conclusions Delayed PCI in AAMI might prevent the late phase but not the early phase of left ventricular remodeling.