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Hypertension
The relationship between brachial-ankle pulse wave velocity and diastolic function in essential hypertensive patients with left ventricular hypertrophy
  1. Chen Gailing,
  2. Wang Yong,
  3. Jiang Hong,
  4. Wang Yun
  1. Department of Cardiology, China-Japan Friendship Hospital, Beijing, China

Abstract

Objective To evaluate the relationship between brachial-ankle pulse wave velocity (baPWV) and left ventricular function in essential hypertensive patients with left ventricular hypertrophy.

Methods A total of 54 hypertensive patients with left ventricular hypertrophy were divided into two groups: E/Ea≥15 group and E/Ea<15 group. Auto-survey atherosclerosis apparatus was applied to examine baPWV and ankle-brachial index (ABI). Central aortic waveforms were generated using pulse wave analysis. End-diastolic left ventricular diameter (LVIDd), interventricular septum thickness (IVSd), end-diastolic posterior wall thickness (LVPWd), left ventricular ejection fraction (LVEF), left ventricular mass index (LVMI) and E, A, Ea were measured by echocardiography.

Results baPWV were significantly higher in the E/Ea ≥15 group compared to the E/Ea <15 group (1844.26±347.90 vs 1616.23±295.08, p<0.05). There were no significant differences in LVEF ABI between the two groups. Correlation analysis revealed that baPWV was significantly and independently associated with E/Ea ((r=0.289, p<0.05)).

Conclusions Elevated baPWV is significantly associated with diastolic function in essential hypertensive patients with left ventricular hypertrophy.

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