Objective To evaluate the relationship between brachial-ankle pulse wave velocity (baPWV) and left ventricular function in essential hypertensive patients with left ventricular hypertrophy.
Methods A total of 54 hypertensive patients with left ventricular hypertrophy were divided into two groups: E/Ea≥15 group and E/Ea<15 group. Auto-survey atherosclerosis apparatus was applied to examine baPWV and ankle-brachial index (ABI). Central aortic waveforms were generated using pulse wave analysis. End-diastolic left ventricular diameter (LVIDd), interventricular septum thickness (IVSd), end-diastolic posterior wall thickness (LVPWd), left ventricular ejection fraction (LVEF), left ventricular mass index (LVMI) and E, A, Ea were measured by echocardiography.
Results baPWV were significantly higher in the E/Ea ≥15 group compared to the E/Ea <15 group (1844.26±347.90 vs 1616.23±295.08, p<0.05). There were no significant differences in LVEF ABI between the two groups. Correlation analysis revealed that baPWV was significantly and independently associated with E/Ea ((r=0.289, p<0.05)).
Conclusions Elevated baPWV is significantly associated with diastolic function in essential hypertensive patients with left ventricular hypertrophy.