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Cardiovascular disease clinical research
GW23-e0693
THE RELATIONSHIP BETWEEN CALCIFICATION OF HEART VALVES AND AGE
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  1. Li Kang1⇓,
  2. Yang Chong-qing2,
  3. Lu An-huai3,
  4. Wang Fang1,
  5. Li Yan3,
  6. Lu An-huai3
  1. 1Department of Cardiology, Beijing Hospital, Beijing 100730, China
  2. 2Department of Pathology, Beijing Hospital, Beijing 100730, China
  3. 3School of Earth and Space Sciences, Peking University, Beijing 100871, China

    Abstract

    Objectives To investigate the relationship between calcification of heart valves and age.

    Methods 966 patients were divided into 6 groups by age: <50 years, 50–60 years, 60–70 years, 70–80 years, 80–90 years and >90 years. All the patients underwent ultrasonic cardiography for assessment of heart valval calcification. The relationship between valval calcification and age was studied by logistic regression analysis.

    Results 1. The incidence of one valve calcification in six groups was 2.6%, 17.0%, 43.4%, 82.3%, 91.7%, 92.2% respectively, the difference between each group had statistical significance(p<0.001);

    2. The incidence of two valves calcification in six groups was 0%, 0%, 1.6%, 7.0%, 18.3%, 31.0% respectively, the difference between each group had statistical significance(p<0.001);

    3. Aging (for each additional 10 years) predicted valve calcification, HR was 3.663 (95% CI 3.108 to 4.317, p<0.001) by single-factor control and 3.223 (95% CI 2.669 to 3.892, p<0.001) by multiple-factors control.

    Conclusions The incidence of heart valve calcification increased by aging, people more than 60 years old were easier to occur heart valve calcification.

    https://doi.org/10.1136/heartjnl-2012-302920s.13

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