Objectives To observe the effect of using flupentixol melitracen (trade name Deanxit) to treat unstable angina patients with anxiety-depression.

Methods 126 unstable angina patients with anxiety/depression were randomly divided into control group (n=60) and deanxit intervention group (n=66). Patients in intervention group were accepted conventional therapy and deanxit 1 or 2 pieces for 4 weeks. To observe the incidence of angina pectoris and malignant cardiovascular events, and the improving of anxiety and depression in both two groups.

Results The angina symptoms and CGI scores of intervention group patients were obviously superior to control group, and the incidence of malignant cardiovascular events were significantly decreased (p<0.05).

Conclusions Deanxit treatment could improve the curative effect of unstable angina, decrease the incidence of short-term malignant cardiovascular events and relieve the symptoms of anxiety and depression.