Objectives The aim of this study was to investigate the value of NT-pro B-type natriuretic peptide (BNP) in the differentiation of acute dyspnoea in the emergency department.
Methods The level of NT- pro BNP of 128 patients, who presented with acute dyspnoea caused by congestive heart failure or non-CHF, were tested by ELISA and compared.
Results The NT-pro BNP level of the patients with dyspnoea caused by CHF were obviously higher than those of patients with non-cardiogenic dyspnoea (p<0.01). The level of NT-pro BNP was significantly different among different stages of heart function in CHF group and without correlation with left ventricular ejection fraction (LVEF).
Conclusions Our results indicate that NT-pro BNP assays have a high degree of diagnostic accuracy and clinical relevance for CHF.