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GW23-e0850
INFLUENCE OF SALT LOADING AND POTASSIUM SUPPLEMENT ON SHORT TERM BLOOD PRESSURE VARIABILITY FOR SALT-SENSITIVITY ADULTS
  1. Yu Chao,
  2. Jianjun Mu,
  3. Haixia Xu,
  4. Keyu Ren,
  5. Shuhui Zheng,
  6. Fuqiang Liu,
  7. Qiufang Lian,
  8. Jianjun Mu
  1. Department of Cardiology, The First Affiliated Hospital of Medical College, Xi'an Jiaotong University

    Abstract

    Objectives To observe the change of short blood pressure variation on salt-sensitive normotensive people after sodium-potassium diet, and explore the relationship between blood pressure variability and salt-sensitivity.

    Methods A baseline survey was carried out in 93 normotensive adults (age>16) in Mei county, Shanxi province from April to October, 2004. All subjects were recruited and sequentially maintained on a protocol with 7 days low salt diet, 7 days high salt diet, and high salt diet with potassium supplementation for another 7 days. We measured blood pressure three times on the last day of each stage, and compute the SD and coefficient of variation as indicator of short term blood pressure variability.

    Results Completed a total of 93 cases, 32.26% for the salt sensitivity. Baseline blood pressure variability of salt-sensitive was larger than salt-resistive group, and there was significant difference on systolic pressure. Salt restriction and potassium supplementation reduced short-term blood pressure variability of salt-sensitivity, while high-salt diet increased blood pressure variation, whereas no obvious changes were observed in non-salt-sensitive group.

    Conclusions High salt intake and salt sensitivity are important risk factors for increasing blood pressure variation. Salt restriction and potassium supplementation may be protective.

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