Objective This study aims to evaluate whether myocardium ischemia induced by treadmill exercise testing (TET) will impact on Tpeak-Tend interval (Tpe).

Methods Record the electrocardiogram of positive and control group before and at the peak of TET, measure and calculate the maximal Tpe, mean Tpe, QT dispersion (QTd) and Tpe of the leads with limited ST-segment deviation.

Results 1. The comparison of the corrected maximal Tpe, mean Tpe and the corrected QTd is much longer at the peak of exercise test in positive group (P < 0.05). Before and at the peak of TET the difference of all above indexes in positive group are significant. 2.Tpe was longer in positive group compared to control group. The comparison of the leads corresponding to local myocardial ischemia in positive group showed Tpe in the peak of TET is longer than Tpe before TET.

Conclusions Maximal, mean Tpe, QTd at the peak of test in positive group and Tpe of the leads with limited ST-segment deviation are significantly longer, prompting that the prolong of Tpe in exercise induced myocardial ischemia may reflect the increasing of ventricular dispersion of repolarization, and may indirectly reflect the myocardia ischemia.