Article Text

PDF
ASSA13-14-6 Effect of Different Body Mass Index and Waist Circumference on Arterial Elasticity in Essential Hypertension
  1. Song Hongbin1,2,
  2. Liu Zhendong1,
  3. Lu Fanghong1,
  4. Diao Yutao1,
  5. Zhang Hua1,
  6. Zhao Yingxin1,
  7. Sun Shangwen1,
  8. Qi Zaiwen1,2
  1. 1Center of Cardiovascular Disease Prevention and Treatment, Institute of Basic Medicine, Shandong Academy of Medical Sciences, Jinan, Shandong 250062, China
  2. 2School of Medicine and Life Sciences, University of Jinan-Shandong Academy of Medical Sciences, Jinan, Shandong 250062, China

Abstract

Objective To investigate the effect of different body mass index (BMI) and waist circumference on arterial elasticity in essential hypertension.

Methods The basic information was collected in a total of 776 essential hypertensive patients. According to BMI and waist circumference level, all patients were divided into four groups, namely, normal BMI and normal waist circumference group (Igroup, n = 194 cases), normal BMI and elevated waist circumference group (IIgroup, n = 195 cases), excessive BMI and normal waist circumference group (III group, n = 196 cases), excessive BMI and elevated waist circumference group (IVgroup, n = 191 cases). Brachial ankle pulse wave velocity (baPWV) and ankle-brachial blood pressure index (ABI) were observed in all patients. Arterial stiffness index (AI) was calculated using the blood lipid of all hypertension patients.

Results baPWV (2120 ± 263) and AI (3.35 ± 0.87) in IV group were significantly higher than Igroup (P < 0.01), IIgroup and III group (P < 0.05). ABI (0.72 ± 0.15) in IV group were significantly lower than Igroup (P < 0.01), IIgroup and III group (P < 0.05). There were no statistical differences between IIgroup and III group in ABI and AI (P > 0.05). Results of 2 × 2 factorial analysis showed that there was a distinctive and synergistic effect between excessive BMI and elevated waist circumference on arterial stiffness.

Conclusions Arterial elasticity function was aggravated damaged in essential hypertension in patients with abdominal obesity. Excessive BMI and elevated waist circumference had interaction and synergistic effect on the damage of arterial elasticity function.

Statistics from Altmetric.com

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.