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ASSA13-14-11 Relationship of High Blood Pressure Patients Between Vitamin D and Fibrinogen
  1. Xu Xinjuan1,
  2. Ruan Yelan1,
  3. Han Lu2,
  4. Liu Yiwen1
  1. 1Department of Hypertension, the First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China
  2. 2Department of Hypertension, Xinjiang Provincial Corps Hospital, Chinese People’s Armed Police Forces, Urumqi, China

Abstract

Objective To investigate the relationship between vitamin D, fibrinogen, white blood cell count and hypertension, find out the correlation of vitamin D and fibrinogen.

Methods Oct.2010 to Oct.2012 hospitalised 326 hypertensive patients and 218 healthy cases were involved. To analysis the differences of fibrinogen, vitamin D and the number of white blood cells status. Then research the correlation of vitamin D and fibrinogen in hypertension group.

Results Compared with the hypertension group and the non-high-blood group, vitamin D, fibrinogen, the number of white blood cells, lymphocytes, neutrophils and lipids, the difference was statistically significant (P < 0.05). To analysis the multiple factors regression, for hypertension, vitamin D is protective factor (B value = 0.186, OR value = 0.83, 95% CI0.795–0.869), but neutrophils, fibrinogen, low density lipoprotein are risk factors (B value were 0.761, 0.173, 0.987, OR value were 2.141, 1.189, 2.128, 95% CI1.445–3.1731, 1.14 1.908, 1.84 3.971). Hypertension group vitamin D and fibrinogen have negative correlation (r = 0.152, P = 0.011).

Conclusions The vitamin D level of hypertension group was higher and the fibrinogen level was lower than the non-hypertensive group. For hypertension, vitamin D is protective factor, while neutrophils and fibrinogen are risk factors. Vitamin D and fibrinogen were negatively correlated in hypertension patients.

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