Objective To investigate the relationship between vitamin D, fibrinogen, white blood cell count and hypertension, find out the correlation of vitamin D and fibrinogen.
Methods Oct.2010 to Oct.2012 hospitalised 326 hypertensive patients and 218 healthy cases were involved. To analysis the differences of fibrinogen, vitamin D and the number of white blood cells status. Then research the correlation of vitamin D and fibrinogen in hypertension group.
Results Compared with the hypertension group and the non-high-blood group, vitamin D, fibrinogen, the number of white blood cells, lymphocytes, neutrophils and lipids, the difference was statistically significant (P < 0.05). To analysis the multiple factors regression, for hypertension, vitamin D is protective factor (B value = 0.186, OR value = 0.83, 95% CI0.795–0.869), but neutrophils, fibrinogen, low density lipoprotein are risk factors (B value were 0.761, 0.173, 0.987, OR value were 2.141, 1.189, 2.128, 95% CI1.445–3.1731, 1.14 1.908, 1.84 3.971). Hypertension group vitamin D and fibrinogen have negative correlation (r = 0.152, P = 0.011).
Conclusions The vitamin D level of hypertension group was higher and the fibrinogen level was lower than the non-hypertensive group. For hypertension, vitamin D is protective factor, while neutrophils and fibrinogen are risk factors. Vitamin D and fibrinogen were negatively correlated in hypertension patients.