Objective To examine whether sex-based differences existed in outcomes after percutaneous coronary interventions (PCIs) in small coronary arteries.
Methods The patient included 1350 patients after PCI divide to two groups depend on sex, which lesions ≤3.0mm in reference vessel diameter between April 2004 and April 2008. Angiopraphic analysis was performed by independent observes. Statistical analysis was performed using SASsoftware. A P value<0.05 was considered statistically significant.
Results (1) clinical characteristics: women who were older had higher rates of angina and comorbid conditions (diabetes mellitus and hypertension) but were less likely to have had prior surgical or percutaneous coronary revascularization procedures. (2) angiographic lesion characteristics: The characteristics were similar except there were significantly more bifurcation lesions, less pre-TIMI grade 3 flow and less procedural success. (3) half-yeas outcomes: there was no significant difference in the rate of MACEs and other supgroups (target lesion revascularization, actual myocardial infarction, restenosis).
Conclusions Women have wores short-term outcomes after PCI when all coronary artery diameters are included. But when wo selected the same coronary artery diameters, women have similar rates of short-term MACEs. So maybe the diameter of coronary artery is the most importance influential factor in Gender Differences.