Objective The profile of postprandial plasma adiponectin and high-sensitivity C-reactive protein (hsCRP) is unclear in young persons and middle-aged men.
Methods This study included 11 young men (18.9 ± 1.7 year) and 11 (40.8 ± 3.8year) body mass indexes (BMI) matched middle –aged men (22.8 ± 4.58 vs 22.7 ± 4.40, NS). The plasma triglyceride (TG) levels were measured before and at 2, 4 and 6 hours after a fat meal, and adiponectin and hsCRP were measured before and 2 hour after fat meal.
Results The fasting TG level was higher in middle-age group than in young group. The postprandial TG levels at 2, 4 and 6h decreased in the young group, but increased in middle age men. The TG-AUC was significantly higher in middle age men than in young men (2.41 ± 1.31 vs –0.84 ± 1.19, h.mmol/L, P < 0.05). The fasting adiponectin and hsCRP levels were similar between two groups. Both groups showed significantly increased postprandial adiponectin and hsCRP levels with similar increase amplitudes, so the postprandial adiponectin and hsCRP levels were also similar.
Conclusions The postprandial TG levels after a fat meal are associated with age. Although middle-aged men have significant higher postprandial TG levels, the 2 h postprandial adiponectin and hsCRP levels are similar to those of the young men.