Objectives To analyse relationship between the concentration of serum uric acid and its risk factors of cardiovascular disease among population of healthy examination.
Methods Totally 24 22 subjects were investigated during physical examination by recording genders and age, measuring height, weight, body mass index (BMI), systolic blood pressure (SBP) and diastolic blood pressure (DBP), concentrations of serum uric acid (SUA), total cholesterol (TC), triglycerides (TG), serum high density lipoprotein cholesterol (HDL-C), serum low density lipoprotein cholesterol (LDL-C) and fasting blood glucose (FBG). We analysed the relationship of concentration of serum uric acid and its influencing factors.
Results The concentration of SUA was (353.75 ± 76.07) μmol/L) in these population, The concentration of SUA was significantly higher in male than in female [(374.11 ± 70.81) μmol/L vs.(256.60 ± 52.44) μmol/L, P < 0.01]. Partial correlation analysis of cardiovascular risk factors with concentration of SUA after controlling for other risk factors. Among male there was a significantly positive correlativity among concentration of SUA and BMI (r’ = 0.193, P < 0.01), DBP (r’ = 0.043, P < 0.01), TG (r’ = 0.141, P < 0.01). Age (r’ = 0.202, P < 0.01), FBG (r’ = 0.071, P < 0.01) were significantly negative correlated with concentration of SUA. There was no correlativity between concentration of SUA and SBP. TC, LDL-C, HDL-C. Among female BMI (r’ = 0.212, P < 0.01)* and LDL-C (r’ = 0.142, P < 0.05) were significantly positively correlated with concentration of SUA, while the rest were no correlativity.
Conclusions Concentration of SUA is high in population of healthy examination. High concentration of SUA is significantly correlated with multiple cardiovascular risk factors.