Objectives To understand the relationship between hyperuricemia and cardiovascular disease risk factors.
Methods 468 cases with hyperuricemia (HUA) screened out from a company on-the-job personnel healthy medical information, and 508 cases with normal serum uric acid levels (NUA) were randomly selected from the same healthy medical information. Two groups of cardiovascular risk factors were compared with. After an accurate clinical examination and a biochemical evaluation, the results were analysed.
Results Participants with hyperuricemia compared to those with normal serum uric acid levels had higher in SBP, DBP, TG, LDL- C and BMI (p < 0.01). Multiple regression analysis showed significant correlation of serum uric acid level and DBP, BMI, TG and fasting glucose levels (p < 0.01 or p < 0.05).
Conclusions Serum uric acid concentration are significantly association with cardiovascular disease (CVD) risk factors, and increase risk of CVD.