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GW24-e2937 Hypertriglyceridemic waist might be an alternative to metabolic syndrome for predicting future diabetes mellitus
  1. Chen Xiaoping,
  2. He Sen,
  3. Wang Yong
  1. Department of Cardiology, West China Hospital, Sichuan University, Chengdu 610041, China

Abstract

Objectives In some cross-sectional studies, hypertriglyceridemic waist (HTGW) has been recommended as an alternative to metabolic syndrome (MetS) for screening individuals at high risk for diabetes mellitus (DM). However, little information is about the predictive power of HTGW for future DM. The aims of the study were to assess the DM predictive power of HTGW compared with MetS based on the follow-up data over 15 years collected from a general Chinese population.

Methods The data were collected in 1992 and then again in 2007 from the same group of 687 individuals without DM in 1992.

Results For the whole population (n = 687), multivariate analysis showed presence of HTGW was associated with a 4.1-fold (95%CI: 2.4–7.0, p < 0.001) increased risk and presence of MetS was associated with a 3.7-fold (95%CI: 2.2–6.2, p < 0.001) increased risk for future DM. For the population without elevated fasting plasma glucose (n = 650), multivariate analysis showed presence of HTGW was associated with a 3.9-fold (95%CI: 2.2–7.0, p < 0.001) increased risk and presence of MetS was associated with a 3.7-fold (95%CI: 2.1–6.6, p < 0.001) increased risk for future DM.

Conclusions HTGW could predict future DM independently, and the predictive power was similar to MetS. HTGW might be an alternative to MetS for predicting future DM. For simpler and fewer components, HTGW might be more practical than MetS, and it might be recommended in most clinical practices.

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