Article Text

GW24-e0032 Study of protection of healthy subjects with Tibetan high-altitude exposure on fibrinolytic system
  1. Yang Bo,
  2. Li Min
  1. PLA General Hospital


Objectives To investigate the changes of fibrinolytic system of healthy subjects with acute high altitude exposure (3 658 m above sea leve1).

Methods A total of 50 young male subjects were enrolled in this study. They were all newly engaged army members recruited from Sichuan province (400 m above sea leve1). The serum levels of prothrombin time (PT), thrombin time (TT), activated partial thromboplastin time (APTT), fibrinogen (Fg), plasminogen (Plg), plasmin inhibitor, D-dimer (DD) were measured before and 3 days after ascending high-altitude

Results After acute high-altitude, PT, TT, APTT, DD increased and FIB, Pig, plasmin inhibitor decreased (P < 0.05).

Conclusions The fihrinolytie system greatly changed in healthy subjects with acute high-altitude exposure.

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