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GW24-e1834 Long term outcome of stent implantation in 48 patients with carotid artery stenosis
  1. Wang Xiao-Zeng,
  2. Han yaling
  1. Department of Cardiology, Institute of Cardiovascular Research of People’s Liberation Army, Shenyang Northern Hospital, Shenyang, Liaoning 110840, China

Abstract

Objectives The aim of this study was to determine the safety and long-term efficacy after stent implantation in patients with carotid artery stenosis.

Methods 48 patients with angiographic confirmed carotid artery stenosis were recruited from January 2005 to Dec 2010. All stents were implanted into carotid artery with guidance of distal cerebral protection device in order to observe perioprative complacations and clinical efficacy.

Results The mean age of all the 48 patients were 66.0 ± 6.8 years, 41 patients (85.4%) were male. There was averagely one target lesion per patient. The stenotic lesions were averagely 22.5 ± 10.3 mm in length and 88.5 ± 9.9% in degree of stenosis. Each lesion underwent 1 self-expanding stent implantation with guidance of distal cerebral protection device. The procedural success rate was 100%. The stent was averagely 7.3 ± 2.4 mm in diameter and 36.0 ± 5.5 mm in length. The degree of immediate postprocedural residual stenosis was 5.6 ± 4.5%. During the procedure, 11 patients (22.9%) patients presented with dropped heart rate, which was restored to normal after administration of 1 mg atropine; 2 patients (4.2%) arouse unilateral limb movement, which was recovered within 24 hours after treatment. No serious postprocedural complications were found. The average follow-up time was 36.2 ± 15.5 months, and follow-up rate was 93.8% (45/48). A total of 2 patients (4.4%) died, including 1 lung cancer and 1 ischaemic stroke. 4 patients (8.9%) were still attacked by dizziness, 3 patients (6.7%) had occasional numbness in limbs. There was no severe cerebral ischaemic attack, cerebral infarction or cerebral haemorrhage. From 6 to 12 months follow-up after operation, enhanced CT scans showed no in-stent restenosis in carotid.

Conclusions With guidance of distal cerebral protection device, carotid artery stenting showed a long-term satisfactory safety and efficacy in carotid stenosis patients as well as high operation success rate.

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