Objectives To detect plasma ADAMTS-7 in acute myocardial infarction patients and the relationship between BNP and ADAMTS-7.
Methods Altogether 42 STEMI (ST elevated myocardial infarction) patients, 30 NSTEMI (non ST elevated myocardial infarction) patients, and 38 controls were included. ELISA was used to measure plasma ADAMTS-7. The relationship between BNP and ADAMTS-7 were calculated by linear corelation.
Results Plasma ADAMTS-7 in STEMI group, NSTEMI group and control group were 5.08 ± 3.35ng/ml, 4.67 ± 3.57 ng/ml and 1.63 ± 1.58 ng/ml respectively. Myocardial infarction group elevated significantly (P < 0.05) than control group. Plasma ADAMTS-7 had positive relations with BNP (P < 0.05).
Conclusions Elevated ADAMTS-7 level may be a mechanism for heart failure in acute myocardial infarction patients.