Objectives To investigate the effect of deanxit on subjects with heart failure secondary to valvular heart disease combined anxiety and depression.
Methods After 60 patients being evaluated by HAMA and HAMD, the positive subjects were followed up for 2 weeks. According to baseline assessments, the patients were randomly divided into experimental group (basic drug trerapy and Deanxit) and control group (only basic drug trerapy). Cardiac function parameters and score of HAMA and HAMD were compared.
Results Compared with control group, Cardiac function improved markedly, the scores of HAMA and HAMD in experiment groups were significantly lower than those before treatment while little changes in the scores of HAMA and HAMD was found in those of the control group.
Conclusions To use Deanxit combined anti - heart failure drugs could gain better synergic effect in the patients of heart failure secondary to valvular heart disease with anxiety and depression.