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GW24-e3549 Role of heart-type fatty acid-binding protein in assessing prognosis of acute pulmonary embolism
  1. Li,
  2. Bingong Li
  1. Department of Cardiology, First Affiliated Hospital, Nanchang University

Abstract

Objectives To study the role of heart-type fatty acid-binding protein (H-FABP) in assessing prognosis of acute pulmonary embolism (APE).

Methods The levels of plasmid H-FABP and cTnI and D-Dimer in 72 patients with APE and 30 healthy controls were determined. The associations between the biomarkers and the severe complications were determined though a logistic regression model.

Results The levels of D-Dimer in patients with APE were significantly higher than that in healthy controls (P < 0.01). The incidence of severe complications in the H-FABP-positive group of APE was higher than in the H-FABP negative group (66.7% vs 3.5%, P < 0.05). By logistic regression, elevated H-FABP was associated with a 50.44-fold increase in the death or complication risk (95%CI: 7.40-342.88, P < 0.001).

Conclusions The H-FABP might be a useful biomarker for prediction prognosis of patients with APE.

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