Objectives Recent studies have demonstrated LGE characteristics had a great role in diagnosis and evaluation of heart disease and provide risk stratification for cardiovascular disease. In the present study, we were sought to explore the prevalence of LGE in a large clinical population and its influence on left ventricular remodelling.
Methods During Jan, 2012 to Mar 2013, a consecutive series of patients with heart disease referred for clinical contrast–enhanced CMR investigation was included this study. Cases with poor image quality or without qualitative ventricular functional data were excluded. LGE prevalence rate was calculated according to different heart disease types. Associations between existence of LGE and LV remodelling parameters were analysed.
Results Five hundred and forty three cases (543; female 202 and male 341) with different heart disease had adequate CMR imaging. The average age was 46.5 ± 19.3 years old. Tthe prevalence of LGE in the whole patients population was 41% and the prevalence of LGE wass significantly different in diverse heart disease classification (P < 0.001). Existence of LGE was associated with significantly decreased LVEF, increased LVEDVI, LEVSVI and LV mass index (P < 0.001). By multivariate Logistic regression analysis, LVEDVI (P < 0.001), LVESVI (P < 0.001), AS (P < 0.001) and LVMASSI (P < 0.001) were demonstrated to be the independent predictors of LGE.
Conclusions LGE was a common characteristic of structural heart disease. It is a strong indicator of bad left ventricular remodelling. It could be possible to use LGE as a new clinical indicator to monitor the remodeling process of LV in heart disease.