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GW24-e0652 Assessment of the ventricular-arterial coupling in the patients with systemic lupus erythematosus by ultrasound
  1. Ruitao Zhou,
  2. Qing Lv
  1. Department of Ultrasonography, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology

Abstract

Objectives The aim of our study is to assess the ventricular-arterial coupling in the patients with systemic lupus erythematosus (SLE) by ultrasound.

Methods Twenty-Five patients with SLE and twenty age and gender matched healthy subjects were studied. Left ventrical mass index (LVMI), relative wall thickness end-diastolic (RWT), carotid-femoral pulse wave velocity (CFPWV), effective arterial elastance (Ea) and Ea/Ees were measured.

Results Ed in the patients SLE were significantly higher than those in control group (P<0.05), there was no significant difference in Ees and Ea/Ees between two groups (p > 0.05). Ed was correlated positively with Ea (r = 0.472, p < 0.01). RWT was correlated positively with Ed and Ea (r = 0.388, P = 0.016; r = 0.336, P = 0.026). Ed was correlated positively with E/e (r = 0.939, P < 0.01). CFPWV was correlated positively with Ed and E/e and LVMI (r = 0.349, p < 0.05; r = 0.376, p < 0.05; r = 0.323, p < 0.05). diffD% was correlated negatively with E/e and LVMI (r = -0.328, p < 0.05; r = -0.428, p < 0.01).

Conclusions The structure and function of left ventricle is associated with arterial elastance. Their matching relation can be applied to evaluate ventricular-arterial coupling.

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