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Long-Term Follow-up of Cardiac Syndrome X Patients Treated by Spinal Cord Stimulation
  1. Gregory A Sgueglia
  1. Catholic University, Rome, Italy
    1. Alfonso Sestito
    1. Catholic University, Rome, Italy
      1. Antonella Spinelli
      1. Catholic University, Rome, Italy
        1. Beatrice Cioni
        1. Catholic University, Rome, Italy
          1. Fabio Infusino
          1. Catholic University, Rome, Italy
            1. Fabio Papacci
            1. Catholic University, Rome, Italy
              1. Fulvio Bellocci
              1. Catholic University, Rome, Italy
                1. Mario Meglio
                1. Catholic University, Rome, Italy
                  1. Filippo Crea
                  1. Catholic University, Rome, Italy
                    1. Gaetano A Lanza (g.a.lanza{at}inwind.it)
                    1. Catholic University, Rome, Italy

                      Abstract

                      Objective To assess the long-term effect of spinal cord stimulation (SCS) in patients with refractory cardiac syndrome X (CSX).

                      Patients and Design We performed a prospective, controlled, long-term follow-up of 19 CSX patients with refractory angina who underwent SCS (SCS group, 5 men, 60.9±8.5 years); 9 comparable CSX patients who refused SCS treatment (3 men, 60.9±8.8 years) constituted the Control group. Clinical and functional status was assessed at the time of screening for SCS indication (basal evaluation) and at a median follow-up of 36 months (range 15-82).

                      Results There were no differences between the 2 groups at baseline in clinical characteristics and angina status. All indicators of angina status (angina episode frequency, duration, and short-acting nitrate use) improved significantly at follow-up in the SCS group (p<0.001) but not in controls. Functional status, as assessed by Seattle Angina Questionnaire and a visual analogical scale for quality of life, improved at follow-up in the SCS group (P<0.001 for all scales) but not in controls. Exercise tolerance and exercise-induced angina and ST segment changes also significantly improved in the SCS group but not in controls.

                      Conclusions Our data show that SCS therapy can be a valid form of treatment for long-term control of angina episodes in patients with refractory CSX.

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