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Randomized comparison of femoral versus radial approach for percutaneous coronary intervention using abxicimab in acute myocardial infarction: Results of the FARMI (Five french Arterial access with Reopro in Myocardial Infarction) Trial.
  1. Camille Brasselet (camille.brasselet{at}wanadoo.fr)
  1. Department of Cardiology, Centre Hospitalier Universitaire Robert Debré, Reims, France
    1. Sophie Tassan-Mangina
    1. Department of Cardiology, Centre Hospitalier Universitaire Robert Debré, Reims, France
      1. Pierre Nazeyrollas
      1. Department of Cardiology, Centre Hospitalier Universitaire Robert Debré, Reims, France
        1. Martial Hamon
        1. Service des Maladies du Coeur et Vaisseaux, Centre Hospitalier Universitaire, Caen, France, France
          1. Damien Metz
          1. Department of Cardiology, Centre Hospitalier Universitaire Robert Debré, Reims, France

            Abstract

            Objective The purpose of the FARMI prospective, randomized trial was to compare bleeding complications and results of PCI between patients treated via radial and femoral approaches in the setting of AMI, and using abciximab and 5 French guiding-catheters.

            Patients A hundred and fourteen consecutive patients suffering from acute myocardial infarction were prospectively randomized. Exclusion criteria were as follows: history of CABG, cardiogenic shock, atrio-ventricular block, and contra-indication to abciximab or negative Allen's test. Local haemostasis was achieved by manual compression.

            Results Baseline characteristics were similar between both groups. Peripheral arterial complication rates and delay to patient ambulation were significantly lower in the radial group as compared to the femoral group, whereas in-hospital stay was similar between both groups. A cross-over was more frequently necessary in the radial group as compared to the femoral group. Coronary angiography duration and fluoroscopy time were significantly longer in the radial group as compared to the femoral group, whereas PCI duration was similar between both.

            Conclusions The FARMI trial showed that radial route lowered peripheral arterial complication rates and allowed earlier ambulation, despite no significant benefit on the duration of hospitalisation.

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