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The impact of gender on outcomes of patients with ST elevation myocardial infarction transported for percutaneous coronary intervention. Analysis of the PRAGUE 1 and 2 studies
  1. Zuzana Motovska (zuzana.motovska{at}iex.cz)
  1. 3rd Medical Faculty of Charles University, Czech Republic
    1. Petr Widimsky
    1. 3rd Medical Faculty of Charles University, Czech Republic
      1. Michael Aschermann
      1. 1st Medical faculty of Charles University, Czech Republic

        Abstract

        Background Data comparing survival outcomes for women vs men transported for pPCI absent.

        Objectives To asses the impact of gender on 30-day mortality of patients with STEMI transported for pPCI.

        Methods. The data from the PRAGUE-1 and PRAGUE-2 trials were analyzed. Studies compared thrombolysis in the community hospital and pPCI after transport to cardiocentre. We analysed a group of 520 patients treated with thrombolysis and 530 transported to pPCI.

        Results Women were older, with a higher risk profile. They had longer ischemia time. Mortality of patients treated with TL was significantly higher in women compared to men (15% vs. 9%, p=0,043). There was no significant gender difference in mortality in the PCI group (8,2% of women vs. 6,2% of men, p=0,409). Mortality of women treated with on-site TL was nearly twice as high as mortality of women transported for pPCI (p=0,043). After adjustment in a multivariate model the odds ratio for mortality in females was 0.74 (95% CI. 0.26-2.05; P=0,556)

        Conclusion Long distance transport of women with STEMI from a community hospital to a tertiary PCI centre is a significantly more effective treatment strategy than on-site TL. Gender did not determine survival in patients transported for pPCI.

        • gender
        • myocardial infarction
        • transport for percutaneous coronary intervention

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