Aim To evaluate if 3D echocardiography (3-DE) is similarly accurate and reproducible as cMR in estimating LV parameters in patients with and without wall motion abnormalities (WMA).
Methods 83 patients (33 with WMA) underwent 3-DE and cMR. 3-DE datasets were analysed using a semi-automatic contour detection algorithm. The accuracy of 3-DE was tested against cMR in the 2 groups of patients. All measurements were made twice by 2 different observers.
Results LV mass by 3-DE was similar to that obtained by cMR (149±42g vs. 148±45g, p=0.67), with small bias (1±28g) and excellent interobserver agreement (-2±31g vs. 4±26g). The 2 measurements were also highly correlated (r=0.94), irrespective of WMA. End-diastolic and end-systolic LV volumes and ejection fraction by 3-DE and cMR were highly correlated (r=0.97, 0.98, 0.94, respectively). Yet, 3-DE underestimated cMR end-diastolic (167±68mL vs. 187±70mL, p<0.001) and end-systolic (88±56mL vs. 101±65mL, p<0.001) volumes, but yielded similar ejection fractions (50±14% vs. 50±16%, p=0.23).
Conclusion 3-DE permits accurate determination of LV mass and volumes irrespective of the presence or absence of WMA. LV parameters obtained by 3-DE are also as reproducible as those obtained by cMR. This suggests that 3-DE can be used to follow-up patients with LV hypertrophy and/or remodeling.
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