Objective: To assess LV strain and displacement and their relations to LV geometry in patients with AS.
Design: Cross-sectional echocardiographic study in patients with aortic stenosis (AS). Peak circumferential, radial and longitudinal strain and radial, longitudinal and transverse displacement were measured by 2D-speckle tracking. Severity of AS was assessed from energy loss index (ELI). LV hypertrophy was present if LV mass/height2.7 ≥46.9/ 49.2 g/m2.7 in women/men and concentric LV geometry if relative wall thickness >0.43. LV geometry was assessed from LV mass/height2.7 and relative wall thickness in combination.
Setting: Department of Heart Disease, Haukeland University Hospital, Bergen, Norway.
Patients: 70 patients with AS (mean age 73±10 years, 54% women).
Main outcome measures: Association of regional and average LV myocardial strain and displacement with LV geometric pattern and degree of AS.
Results: Average longitudinal strain was lower in the hypertrophy groups and correlated with higher LV mass index and relative wall thickness, lower stress-corrected midwall shortening and smaller ELI (all p <0.05). Average strain and displacement in other directions did not differ between geometric groups. In multivariate regression analysis, lower average longitudinal strain was associated with higher relative wall thickness (β =0.15), lower EF (β =-0.16), systolic blood pressure (β =-0.16) and energy loss index (β =-0.20) (all p <0.05) (R2 =0.72). Replacing relative wall thickness with LV mass, lower longitudinal strain was also associated with higher LV mass (β =0.21, p <0.05) (R2 =0.73).
Conclusions: In patients with AS, lower average longitudinal strain is related to higher LV mass, concentric geometry and more severe AS.
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