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Lone Atrial Fibrillation - What Do We Know?
  1. Dariusz Kozlowski
  1. Department of Cardiology and Electrotherapy, Medical University of Gdansk, Poland
    1. Szymon Budrejko
    1. Department of Cardiology and Electrotherapy, Medical University of Gdansk, Poland
      1. Gregory Y H Lip
      1. University Department of Medicine, City Hospital, Birmingham, United Kingdom
        1. Jacek Rysz
        1. Department of Nephrology, Hypertension and Family Medicine, Medical University of Lodz, Poland
          1. Dimitri P Mikhailidis
          1. Department of Clinical Biochemistry, University College London, United Kingdom
            1. Grzegorz Raczak
            1. Department of Cardiology and Electrotherapy, Medical University of Gdansk, Poland
              1. Maciej Banach (maciejbanach{at}aol.co.uk)
              1. Department of Hypertension, Medical University of Lodz, Poland

                Abstract

                Atrial fibrillation (AF) is the most common arrhythmia encountered in clinical practice. Despite the common association of AF with cardiovascular disease, some patients can be classified as ‘lone AF’. The latter is essentially a diagnosis of exclusion, and should be preceded by careful evaluation, including thorough collection of medical history, physical examination, blood pressure measurement, laboratory tests, ECG, echocardiography and possibly, chest x-ray and exercise testing. Lone AF patients were initially thought to have a good prognosis with respect to thromboembolism and mortality, compared with the general AF population, but more recent data suggest otherwise.

                This review focuses on the clinical epidemiology and management aspects of lone AF, as well as various associated novel risk factors, such as familial, genetic and socioeconomic factors, alcohol, sports activity and biochemical markers.

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