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Reduction of blood pressure already in the normal range further regresses left ventricular mass
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To the Editor: We read with interest the paper by Simpson and colleagues describing a reduction in left ventricular (LV) mass among predominantly hypertensive subjects with left ventricular hypertrophy (LVH) despite blood pressure being within the normal range on entry.1 Further lowering of systolic blood pressure (SBP) by 9.3 (8.6) mmHg resulted in a reduction of LV mass index by 4.7 (7.3) g. We have recently demonstrated a comparable drop in LV mass in normotensive (<130/80 mmHg) patients with early chronic kidney disease and normal LV mass at baseline …