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We thank Magnino and colleagues for their interest in our paper1 and appreciate their comments. Their three concerns relate to the assessment of left ventricular (LV) filling pressure, the calculation of right atrial pressure (RAP) and the choice of selection of the original estimation (echocardiographic estimation of pulmonary vascular resistance (PVRe))2 versus our proposed corrected estimation (PVRc).
Although imperfect, E/e' is one of the best available noninvasive tissue Doppler-based parameters for estimating LV filling pressures.3 …
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