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Titration of antihypertensive agents after their initiation: an important clinical issue now addressed
  1. Johnny Yu Jiang1,
  2. Martin C S Wong2
  1. 1Chinese Academy of Medical Sciences and Peking Union Medical College, DongCheng District, Beijing, China
  2. 2School of Public Health and Primary Care, Faculty of Medicine, Chinese University of Hong Kong; Prince of Wales Hospital, Shatin, NT, Hong Kong SAR, China
  1. Correspondence to Martin CS Wong, School of Public Health and Primary Care, Faculty of Medicine, Chinese University of Hong Kong; Prince of Wales Hospital, Shatin, NT, Hong Kong SAR, China; wong_martin{at}cuhk.edu.hk

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The prevalence of hypertension in the USA has already reached >30% in the years 2005–8, but its control rate remains poor at approximately 40% in the same calendar years.1 Similarly low proportions of hypertensive patients achieving optimal blood pressure targets were observed in other countries, despite substantial evidence indicating the effectiveness of antihypertensive agents in reducing cardiovascular risks.2–4 A recent survey conducted in rural China found that 43.8% had hypertension, and among hypertensive patients only 26.2% and 22.2%, respectively, were aware of, and currently undergoing, antihypertensive treatment. Only 3.9% achieved optimal blood pressure control.5 The American Heart Association estimated that the direct and indirect costs of hypertension per year are more than 93.5 billion dollars, and cardiovascular diseases including stroke contributed …

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