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Original research article
Trial registration and adherence to reporting guidelines in cardiovascular journals
  1. Matt Thomas Sims,
  2. Aaron Marc Bowers,
  3. Jamie Morgan Fernan,
  4. Kody Duane Dormire,
  5. James Murphy Herrington,
  6. Matt Vassar
  1. College of Osteopathic Medicine, Oklahoma State University Center for Health Sciences, Tulsa, Oklahoma, USA
  1. Correspondence to Aaron Marc Bowers, Oklahoma State University Center for Health Sciences, Tulsa, OK 74074, USA; Aaron.Bowers{at}okstate.edu

Abstract

Objective This study investigated the policies of cardiac and cardiovascular system journals concerning clinical trial registration and guideline adoption to understand how frequently journals use these mechanisms to improve transparency, trial reporting and overall study quality.

Methods We selected the top 20 (by impact factor) journals cited in the subcategory ‘Cardiac and Cardiovascular Systems’ of the Expanded Science Citation Index of the 2014 Journal Citation Reports to extract journal policies concerning the 17 guidelines we identified. In addition, trial and systematic review registration adherence statements were extracted. 300 randomised controlled trials published in 2016 in the top 20 journals were searched for clinical trial registry numbers and CONSORT diagrams.

Results Of the 19 cardiac and cardiovascular system journals included in our analysis, eight journals (42%) did not require or recommend trial or review registration. Seven (37%) did not recommend or require a single guideline within their instructions to authors. Consolidated Standards for Reporting Trials guidelines (10/19, 53%) were recommended or required most often. Of the trials surveyed, 122/285 (42.8%) published a CONSORT diagram in their manuscript, while 236/292 (80.8%) published a trial registry number.

Discussion Cardiac and cardiovascular system journals infrequently require, recommend or enforce the use of reporting guidelines. Furthermore, too few require or enforce the use of clinical trial registration. Cardiology journal editors should consider guideline adoption due to their potential to limit bias and increase transparency.

  • statistics and study design
  • medical ethics
  • research approaches

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Footnotes

  • Contributors MTS developed the protocol, and contributed to data extraction, writing the manuscript, making tables, editing and revision. AMB contributed to data extraction, making figures, writing, revising and submitting the manuscript. KDD and JMF extracted data. JH and MV oversaw the project and contributed to writing and edits.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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