Featured editorial

	NSAIDs and cardiovascular disease Paola Patrignani, Marta L Capone, and Stefania Tacconelli Heart 2008; 94: 395-397. doi:10.1136/hrt.2007.136002 [Extract] [Full text] [PDF] [Request Permissions]

Editorials

	Risk prediction in pericarditis: who to keep in hospital? David H Spodick Heart 2008; 94: 398-399. doi:10.1136/hrt.2006.113902 [Extract] [Full text] [PDF] [Request Permissions]
	Ejection fraction: a measure of desperation? Charlotte H Manisty and Darrel P Francis Heart 2008; 94: 400-401. doi:10.1136/hrt.2007.118976 [Extract] [Full text] [PDF] [Request Permissions]
	Arrhythmic substrate Marek Malik Heart 2008; 94: 402-403. doi:10.1136/hrt.2007.124198 [Extract] [Full text] [PDF] [Request Permissions]
	Assessment of right ventricular function Lynne Williams and Michael Frenneaux Heart 2008; 94: 404-405. doi:10.1136/hrt.2007.130021 [Extract] [Full text] [PDF] [Request Permissions]
	Social inequalities and cardiovascular disease in South Asians Justin Zaman and Eric Brunner Heart 2008; 94: 406-407. doi:10.1136/hrt.2007.127480 [Extract] [Full text] [erratum] [PDF] [Request Permissions]

Global burden of cardiovascular disease

	Coronary artery disease epidemic in Pakistan: more electrocardiographic evidence of ischaemia in women than in men T H Jafar, Z Qadri, and N Chaturvedi Heart 2008; 94: 408-413. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 23 July 2007. doi:10.1136/hrt.2007.120774

Journal scan

	JournalScan Alistair Lindsay Heart 2008; 94: 535-536. [Extract] [Full text] [PDF] [Request Permissions]

Viewpoints

	Left ventricular ejection fraction: are the revised cut-off points for defining systolic dysfunction sufficiently evidence based? G Mahadevan, R C Davis, M P Frenneaux, F D R Hobbs, G Y H Lip, J E Sanderson, and M K Davies Heart 2008; 94: 426-428. doi:10.1136/hrt.2007.123877 [Extract] [Full text] [PDF] [Request Permissions]

Coronary artery disease

	Plaque characterisation by Virtual Histology intravascular ultrasound analysis in patients with type 2 diabetes K Nasu, E Tsuchikane, O Katoh, H Fujita, J-F Surmely, M Ehara, Y Kinoshita, N Tanaka, T Matsubara, Y Asakura, K Asakura, M Terashima, and T Suzuki Heart 2008; 94: 429-433. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 23 July 2007. doi:10.1136/hrt.2007.118950
	Beneficial effects of aggressive low-density lipoprotein cholesterol lowering in women with stable coronary heart disease in the Treating to New Targets (TNT) study N K Wenger, S J Lewis, F K Welty, D M Herrington, V Bittner on behalf of the TNT Steering Committee and Investigators Heart 2008; 94: 434-439. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 10 December 2007. doi:10.1136/hrt.2007.122325

Cardiac imaging and non-invasive imaging

	Feasibility and clinical decision-making with 3D echocardiography in routine practice J L Hare, C Jenkins, S Nakatani, A Ogawa, C-M Yu, and T H Marwick Heart 2008; 94: 440-445. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 30 July 2007. doi:10.1136/hrt.2007.123570

Heart failure and cardiomyopathy

	A novel mechanism of heart failure with normal ejection fraction D H MacIver and M Townsend Heart 2008; 94: 446-449. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 4 May 2007. doi:10.1136/hrt.2006.114082
	Pulmonary embolism causes endomyocarditis in the human heart M P V Begieneman, F R W van de Goot, I A C van der Bilt, A Vonk Noordegraaf, M D Spreeuwenberg, W J Paulus, V W M van Hinsbergh, F C Visser, and H W M Niessen Heart 2008; 94: 450-456. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 23 July 2007. doi:10.1136/hrt.2007.118638

Endothelial function

Chronic treatment with tetrahydrobiopterin reverses endothelial dysfunction and oxidative stress in hypercholesterolaemia F Cosentino, D Hürlimann, C Delli Gatti, R Chenevard, N Blau, N J Alp, K M Channon, M Eto, P Lerch, F Enseleit, F Ruschitzka, M Volpe, T F Lüscher, and G Noll Heart 2008; 94: 487-492. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 4 October 2007. doi:10.1136/hrt.2007.122184

Epidemiology

	Evaluation of the association between the first observation and the longitudinal change in C-reactive protein, and all-cause mortality C J Currie, C D Poole, and P Conway Heart 2008; 94: 457-462. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 29 August 2007. doi:10.1136/hrt.2007.118794
	Trends for coronary heart disease and stroke mortality among migrants in England and Wales, 1979–2003: slow declines notable for some groups S Harding, M Rosato, and A Teyhan Heart 2008; 94: 463-470. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 9 August 2007. doi:10.1136/hrt.2007.122044
	Smoking status, sports participation and mortality from coronary heart disease H Noda, H Iso, H Toyoshima, C Date, A Yamamoto, S Kikuchi, A Koizumi, T Kondo, Y Watanabe, Y Wada, Y Inaba, A Tamakoshi, and JACC Study Group Heart 2008; 94: 471-475. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 4 October 2007. doi:10.1136/hrt.2007.126458
	Cardiovascular disease mortality in relation to childhood and adulthood socioeconomic markers in British South Asian men T Tillin, N Chaturvedi, N G Forouhi, G D Smith, and P M McKeigue Heart 2008; 94: 476-481. [Abstract] [Full text] [web only tables] [PDF] [Request Permissions]   Published Online First: 23 July 2007. doi:10.1136/hrt.2006.109165
	Rose angina predicts 23-year coronary heart disease mortality in women and men aged 40–49 years S Graff-Iversen, R Selmer, and M-L Løchen Heart 2008; 94: 482-486. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 30 July 2007. doi:10.1136/hrt.2007.115931

Reviews

	Medical treatment of Marfan syndrome: a time for change A Williams, S Davies, A G Stuart, D G Wilson, and A G Fraser Heart 2008; 94: 414-421. doi:10.1136/hrt.2006.109454 [Abstract] [Full text] [PDF] [Request Permissions]

Cardiovascular surgery

	Women’s Recovery from Sternotomy-Extension (WREST-E) study: examining long-term pain and discomfort following sternotomy and their predictors K M King, M Parry, D Southern, P Faris, and R T Tsuyuki Heart 2008; 94: 493-497. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 16 July 2007. doi:10.1136/hrt.2007.117606

Pericardial disease

	Myopericarditis versus viral or idiopathic acute pericarditis M Imazio, E Cecchi, B Demichelis, A Chinaglia, S Ierna, D Demarie, A Ghisio, F Pomari, R Belli, and R Trinchero Heart 2008; 94: 498-501. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 17 June 2007. doi:10.1136/hrt.2006.104067

Rapid communication

	Telomere length is shorter in healthy offspring of subjects with coronary artery disease: support for the telomere hypothesis S W Brouilette, A Whittaker, S E Stevens, P van der Harst, A H Goodall, and N J Samani Heart 2008; 94: 422-425. doi:10.1136/hrt.2007.139675 [Abstract] [Full text] [PDF] [Request Permissions]

Technology and guidelines

	Clinical indications for genetic testing in familial sudden cardiac death syndromes: an HRUK position statement Heart Rhythm UK Familial Sudden Death Syndromes Statement Development Group Heart 2008; 94: 502-507. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 30 July 2007. doi:10.1136/hrt.2007.127761

Featured correspondence

	Impact of blood pressure on the Doppler echocardiographic assessment of severity of aortic stenosis Katerina Linhartova Heart 2008; 94: 508. [Extract] [Full text] [PDF] [Request Permissions]
	The authors’ reply I G Burwash, S H Little, and K L Chan Heart 2008; 94: 508. [Extract] [Full text] [PDF] [Request Permissions]
	Prolonged QRS and QTc interval and mortality F Grigioni, G Piovaccari, and G Boriani Heart 2008; 94: 508-509. [Extract] [Full text] [PDF] [Request Permissions]
	The authors’ reply T Breidthardt and C Mueller Heart 2008; 94: 509. [Extract] [Full text] [PDF] [Request Permissions]

Education in Heart

	The use of cardiac magnetic resonance imaging to determine the aetiology of left ventricular disease and cardiomyopathy Tjeerd Germans and Albert C van Rossum Heart 2008; 94: 510-518. doi:10.1136/hrt.2007.122770 [Extract] [Full text] [PDF] [Request Permissions] BMJ Learning: Take this module on BMJ Learning
	Management of the elderly patient with aortic stenosis Bernard Iung Heart 2008; 94: 519-524. doi:10.1136/hrt.2007.122804 [Extract] [Full text] [web only references] [PDF] [Request Permissions] BMJ Learning: Take this module on BMJ Learning
	Anthracycline associated cardiotoxicity in survivors of childhood cancer Steven E Lipshultz, Jorge A Alvarez, and Rebecca E Scully Heart 2008; 94: 525-533. doi:10.1136/hrt.2007.136093 [Extract] [Full text] [PDF] [Request Permissions] BMJ Learning: Take this module on BMJ Learning

Summary of electronic pages

	These papers are available in full in the electronic pages of this issue of Heart Heart 2008; 94: 534. [Extract] [Full text] [PDF] [Request Permissions]

Electronic pages

	Workload at the heart rate of 100 beats/min and mortality in middle-aged men with known or suspected coronary heart disease K P Savonen, T A Lakka, J A Laukkanen, T H Rauramaa, J T Salonen, and R Rauramaa Heart 2008; 94: e14. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 4 October 2007. doi:10.1136/hrt.2007.123471
	Load-sensitivity of regional tissue deformation in the right ventricle: isovolumic versus ejection-phase indices of contractility C Missant, S Rex, P Claus, L Mertens, and P F Wouters Heart 2008; 94: e15. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 8 August 2007. doi:10.1136/hrt.2006.109520
	Significance of Wedensky Modulation testing in the evaluation of non-invasive risk stratification for ventricular tachyarrhythmia in patients with coronary artery disease and implantable cardioverter-defibrillator N Elgarhi, J Kreuz, O Balta, G Nickenig, H Hoium, T Lewalter, and J Otto Schwab Heart 2008; 94: e16. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 16 July 2007. doi:10.1136/hrt.2006.112730
	Implantable loop recorder in unexplained syncope: classification, mechanism, transient loss of consciousness and role of major depressive disorder in patients with and without structural heart disease T Pezawas, G Stix, J Kastner, B Schneider, M Wolzt, and H Schmidinger Heart 2008; 94: e17. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 18 October 2007. doi:10.1136/hrt.2007.116616

Miscellanea

	Arthritis drugs are hazardous for high risk patients Heart 2008; 94: 403. [Extract] [Full text] [PDF] [Request Permissions]
	Images in Cardiology: An interesting presentation of antiphospholipid syndrome S Aldous Heart 2008; 94: 421. doi:10.1136/hrt.2007.121210 [Extract] [Full text] [PDF] [Request Permissions]
	Images in Cardiology: Bubbles in the left cardiac cavities after diving A Boussuges, J E Blatteau, and J M Pontier Heart 2008; 94: 445. doi:10.1136/hrt.2006.109439 [Extract] [Full text] [web only media] [PDF] [Request Permissions]
	Images in Cardiology: Acute renal artery embolism treated with a cardiac thrombectomy catheter C Critoph, J Radvan, and D Shepherd Heart 2008; 94: 462. doi:10.1136/hrt.2007.115618 [Extract] [Full text] [PDF] [Request Permissions]
	WEB TOP 10 Heart 2008; 94: 492. [Extract] [Full text] [PDF] [Request Permissions]