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Cited by (33)
Management of Anticoagulant and Antiplatelet Agents in Acute Gastrointestinal Bleeding and Prevention of Gastrointestinal Bleeding
2024, Gastrointestinal Endoscopy Clinics of North AmericaCan old dogs learn new "transfusion requirements in critical care": A survey of packed red blood cell transfusion practices among members of the American Association for the Surgery of Trauma
2015, American Journal of SurgeryCitation Excerpt :As for institutional PRBC transfusion guidelines, 57% of respondents' institutions had one. Based on the TRICC trial, current recommendations including the 2012 American Association of Blood Banks guidelines support a transfusion trigger of less than or equal to 7 g/dL in critically ill patients with euvolemia after initial treatment, with the possible exception of those patients with acute myocardial infarction or unstable angina.1,13–18 That being said, several surveys from other countries have documented that this practice has not been widely implemented.4–6
Emergency Management of Major Upper Gastrointestinal Hemorrhage in Children
2010, Clinical Pediatric Emergency MedicineCitation Excerpt :The vigor of resuscitation should be proportional to the severity of bleeding, and inadequate volume resuscitation will be to the patient's detriment.17 Maintenance of the hemoglobin and hematocrit at modest levels (hemoglobin approximately 100 g/L, hematocrit approximately 25%) is suggested; excessive blood transfusion and intravascular volume overexpansion could exacerbate the already increased splanchnic venous pressure and further contribute to variceal bleeding.36 A randomized trial comparing liberal with restricted transfusion practice is currently underway in adults.37
Blood Products, Volume Control, and Renal Support in the Coagulopathy of Liver Disease
2009, Clinics in Liver DiseaseCitation Excerpt :Use of plasma transfusion has led to higher red cell transfusion requirements in liver transplantation at a single European center,33 but these results are hard to consider alone given that numerous factors affect transfusion needs in transplantation. Two additional human studies in patients who had cirrhosis showed that improved oxygen regulation after blood transfusion for anemia has beneficial homeostatic effects on portal vasomotor tone.34,35 These findings support the hypotheses that plasma, in addition to its higher risk for TRALI, may provide fewer beneficial hemodynamic effects than blood transfusion and other volume expanders, with the caveat that overtransfusion after hemorrhage is likely harmful in patients who have cirrhosis.
Cirrhotic cardiomyopathy
2007, Digestive and Liver DiseaseCitation Excerpt :In this way, large volume paracentesis may restore both systolic and diastolic ventricular function in decompensated cirrhotics [16,18], and albumin administration has been reported to improve cardiac output as well as right atrium, pulmonary artery and left ventricular tele-diastolic pressures in patients with cirrhosis and spontaneous bacterial peritonitis [151]. Blood transfusions [152] and infusion of isotonic saline [153] or other plasma expanders such as dextran [102] did not, however, grant comparable results on the cardiac performance, while the central expansion by means of hyperosmotic solutions resulted in an increase of cardiac output [154]. These inconsistencies may be due to the limited pre-load reserve of cirrhotic patients and their decreased ability to modulate cardiac performance under various loading conditions.