Amplitudes, Durations, and Timings of Apically Directed Left Ventricular Myocardial Velocities: I. Their Normal Pattern and Coupling to Ventricular Filling and Ejection☆,☆☆,★
Section snippets
Study Subjects
Twenty healthy normal volunteers with no history of cardiac disease or any cardiovascular symptoms or signs were prospectively recruited for the study. All had normal sinus rhythm. None of the patients was taking any cardiovascular medications. All had normal two-dimensional and Doppler echocardiographic examinations with normal cardiac chamber size and ventricular and valvular functions. The mean ± SD age was 44 ± 16 years (range 25 to 72) years, and two of the volunteers were women.
Recording of Echocardiograms
The
Reproducibility of myocardial velocity measurements
The correlation coefficient for the independent measurements of myocardial velocity amplitudes by the same observer was 0.96 and by different observers was 0.95, and that for durations was 0.97 and 0.95, respectively. With the Bland-Altman method the mean difference between observations was <5% of the mean value of the observations for measurement of both amplitudes and durations.
Mitral and Aortic Flow
The baseline data of the timings and durations of the mitral and aortic flow velocity signals are summarized in
Discussion
Results of this study indicate that in individuals with no clinical or echocardiographic evidence of heart disease, (1) regional differences exist in the long-axis myocardial velocities and extent of shortenings and lengthenings among the four LV walls, (2) differences exist in the amount of early and late diastolic lengthening among the four walls, (3) myocardial velocity gradients exist along the LV long axis, the apex being fairly stationary, and (4) a close coupling of the myocardial
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Cited by (117)
Diastolic Function in Children and in Children With Congenital Heart Disease
2020, Diastology: Clinical Approach to Heart Failure with Preserved Ejection FractionAssessment of Myocardial Ischemic Memory Using Three-Dimensional Speckle-Tracking Echocardiography: A Novel Integrated Analysis of Early Systolic Lengthening and Postsystolic Shortening
2019, Journal of the American Society of EchocardiographyCitation Excerpt :The European Association of Cardiovascular Imaging/American Society of Echocardiography Strain Standardization Task Force has recently reported a significantly lower accuracy for detecting regional functional abnormalities in the basal segments.25 Although myocardial dyssynchrony is small in normal subjects,26 ESL and PSS are observed even in the normal myocardium, and their frequencies are different among segments.14 Physiologic ESL and PSS values may reduce the specificity for detecting ischemic memory.
Left ventricular diastolic function assessment using time differences between mitral annular velocities and transmitral inflow velocities in patients with heart failure
2015, Heart Lung and CirculationCitation Excerpt :In the presence of impaired relaxation and progressive development of HF, there is a delay from the time blood enters the LV inflow tract until filling of the apex. Some studies have demonstrated that mitral annular motion velocity (E’) from tissue Doppler imaging is associated with conventional transmitral flow velocity (E) [20–29] and LV recoil. [30] The study by Bukachi et al. [7] showed that both peak E and peak E’ prolonged, but EDTD did not change significantly in elderly group compared with younger patients.
Ultra-high frame rate tissue doppler imaging
2014, Ultrasound in Medicine and BiologyUse of echocardiography to evaluate the cardiac effects of therapies used in cancer treatment: What do we know?
2012, Journal of the American Society of Echocardiography
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From the Sections of Cardiology, Jerry L. Pettis VA Medical Center and Loma Linda University School of Medicine.
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Reprint requests: Ramdas G. Pai, MD, FRCP(E), Cardiology (111C), Jerry L. Pettis VA Hospital, 11201 Benton St., Loma Linda, CA 92357.
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