Clinical Research
Coronary Artery Disease
Coronary Heart Disease Mortality Among Young Adults in the U.S. From 1980 Through 2002: Concealed Leveling of Mortality Rates

https://doi.org/10.1016/j.jacc.2007.05.056Get rights and content
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Objectives

The objective of our study was to examine age-specific mortality rates from coronary heart disease (CHD), particularly those among younger adults.

Background

Trends for obesity, diabetes, blood pressure, and metabolic syndrome among young adults raise concerns about the mortality rates from CHD in this group.

Methods

We used mortality data from 1980 to 2002 to calculate age-specific mortality rates from CHD for U.S. adults age ≥35 years.

Results

Overall, the age-adjusted mortality rate decreased by 52% in men and 49% in women. Among women age 35 to 54 years, the estimated annual percentage change (EAPC) in mortality was −5.4% (95% confidence interval [CI] −5.8 to −4.9) from 1980 until 1989, −1.2% (95% CI −1.6 to −0.8) from 1989 until 2000, and 1.5% (95% CI −3.4 to 6.6) from 2000 until 2002. Among men age 35 to 54 years, the EAPC in mortality was −6.2% (95% CI −6.4 to −5.9) from 1980 until 1989, −2.3% (95% CI −2.6 to −2.1) from 1989 until 2000, and −0.5% (95% CI −3.7 to 2.9) from 2000 until 2002. Among women and men age ≥55 years, the estimated annual percentage decrease in mortality from CHD accelerated in more recent years compared with earlier periods.

Conclusions

The mortality rates for CHD among younger adults may serve as a sentinel event. Unfavorable trends in several risk factors for CHD provide a likely explanation for the observed mortality rates.

Abbreviations and Acronyms

CHD
coronary heart disease
CI
confidence interval
EAPC
estimated annual percentage change
ICD
International Classification of Diseases

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The findings and conclusions in this article are those of the authors and do not represent the views of the Centers for Disease Control and Prevention.