Chest
Volume 114, Issue 5, Supplement, November 1998, Pages 579S-589S
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Antithrombotic Therapy in Atrial Fibrillation

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Study Design

During the last decade, many studies assessing the efficacy of antithrombotic therapy for the prevention of stroke in AF have been published7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19 (Table 1, Table 2, Table 3, Table 4). Six of the studies were randomized controlled trials comparing oral anticoagulation with control.7,14, 15, 16, 17, 18 The first Atrial Fibrillation, Aspirin, and Anticoagulation Study (AFASAK1), the first Stroke Prevention in Atrial Fibrillation Study (SPAF1), and the

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