Churg-Strauss syndrome with critical endomyocardial fibrosis: 10 year survival after combined surgical and medical management

Heart. 2002 May;87(5):E5. doi: 10.1136/heart.87.5.e5.

Abstract

A case is presented of the Churg-Strauss syndrome with hypereosinophilia and severe cardiac involvement, namely biventricular endomyocardial fibrosis and gross encroachment of the right ventricular cavity. The clinical picture was similar to Loeffler's syndrome and the idiopathic hypereosinophilic syndrome. Combined aggressive surgical and medical management led to full recovery and survival at 10 years. The good long term outcome is attributed to strict control of peripheral eosinophil count by oral corticosteroids. This case illustrates the damaging effects of hypereosinophilia on the heart.

Publication types

  • Case Reports

MeSH terms

  • Churg-Strauss Syndrome / complications*
  • Churg-Strauss Syndrome / drug therapy
  • Churg-Strauss Syndrome / surgery
  • Drug Therapy, Combination
  • Echocardiography / methods
  • Endomyocardial Fibrosis / drug therapy
  • Endomyocardial Fibrosis / etiology*
  • Endomyocardial Fibrosis / surgery
  • Female
  • Humans
  • Hypereosinophilic Syndrome / complications*
  • Hypereosinophilic Syndrome / drug therapy
  • Middle Aged
  • Survivors
  • Treatment Outcome