@article {Denbow536, author = {C E Denbow and E E Chung and G R Serjeant}, title = {Pulmonary artery pressure and the acute chest syndrome in homozygous sickle cell disease.}, volume = {69}, number = {6}, pages = {536--538}, year = {1993}, doi = {10.1136/hrt.69.6.536}, publisher = {BMJ Publishing Group Ltd}, abstract = {OBJECTIVE--To investigate whether attacks of acute chest syndrome affected pulmonary artery pressure in patients homozygous for sickle cell disease. MAIN OUTCOME MEASURES--Pulmonary artery pressure, assessed by non-invasive echocardiographic techniques. PATIENTS--20 patients with homozygous sickle cell disease with a history of at least six episodes of acute chest syndrome and in 20 age, sex, and height matched controls with homozygous sickle cell disease without a history of acute chest syndrome. RESULTS--There was no difference in any of the echocardiographic or Doppler indices between these two groups. CONCLUSIONS--Repeated attacks of acute chest syndrome by the mean age of 12 (range eight to 16) years have not had a discernible effect upon pulmonary artery pressure.}, issn = {0007-0769}, URL = {https://heart.bmj.com/content/69/6/536}, eprint = {https://heart.bmj.com/content/69/6/536.full.pdf}, journal = {Heart} }