Abnormal haemodynamic findings in monochorionic diamniotic twin fetuses with and without twin-twin transfusion syndrome
| Finding | Twin 1 (n=88) | Twin 2 (n=89) | Recipient (n=42) | Donor (n=45) | p Value (R v D) |
|---|---|---|---|---|---|
| One twin 1, five recipients, and two donors were excluded owing to intrauterine demise before to fetal echocardiography. One twin and one recipient were excluded because of structural heart defects (pulmonary valve stenosis and pulmonary atresia with intact septum, respectively). | |||||
| AREDF, absence or reversal of end diastolic flow; D, donor twin; DV, venous duct; MR, mitral regurgitation; R, recipient twin; TR, tricuspid regurgitation; UA, umbilical artery; UV, umbilical vein. | |||||
| Hypertrophy | 1 (1.1%) | 0 (0%) | 24 (57.1%) | 3 (6.7%) | <0.0001 |
| Abnormal function | 0 (0%) | 0 (0%) | 8 (19.0%) | 3 (6.7%) | 0.11 |
| Significant MR | 0 (0%) | 0 (0%) | 6 (14.3%) | 0 (0%) | 0.01 |
| Significant TR | 1 (1.1%) | 0 (0%) | 10 (23.8%) | 2 (4.4%) | 0.01 |
| UA AREDF | 0 (0%) | 3 (3.4%) | 3 (7.1%) | 10 (22.2%) | 0.07 |
| DV AREDF | 0 (0%) | 0 (0%) | 9 (21.4%) | 1 (2.2%) | 0.006 |
| Fetal hydrops | 0 (0%) | 0 (0%) | 2 (4.8%) | 0 (0%) | 0.23 |
| UV pulsations | 0 (0%) | 0 (0%) | 5 (11.9%) | 0 (0%) | 0.02 |