Prevalence of histopathological features found in endoluminal pulmonary thromboendarterectomy material from patients with chronic thromboembolic pulmonary hypertension (n=32), and in the pulmonary arteries of lungs excised at transplantation from patients with thromboembolic (n=7) and plexogenic pulmonary hypertension (n=31)
| Feature | CTEPH | PPH | ES | ES with thrombus |
|---|---|---|---|---|
| Values are n (%). | ||||
| CTEPH, chronic thromboembolic pulmonary hypertension; ES, Eisenmenger syndrome; PPH, primary pulmonary hypertension. | ||||
| n | 39 | 9 | 19 | 3 |
| Fibrocellular tissue 1 | 39 (100) | 9 (100) | 19 (100) | All |
| Organising thrombus | 34 (87) | 0 | 0 | All |
| Recent thrombotic material | 33 (84.6) | 0 | 0 | All |
| Calcification | 18 (46.1) | 0 | 0 | 1/3 |
| Vascular neogenesis | 37 (94.8) | 0 | 0 | 2/3 |
| Macrophages and foam cells | 33 (84.6) | 9 (100) | 18 (94.7) | All |
| Lymphocytes | 34 (87) | 9 (100) | 18 (94.7) | All |
| Pultaceous material | 24 (61.5) | 0 | 0 | All |
| Cholesterol clefts | 24 (61.5) | 1 (11.1) | 1 (5.2) | All |
| Cholesterol clefts in thrombus | 12 (30.7) | 0 | 0 | 2/3 |