Changes in QT indices during treatment phases in the 10 patients
| Baseline (mean (SD)) | Placebo (mean(SD)) | Amiloride (mean(SD)) | Changes between placebo and amiloride | |
|---|---|---|---|---|
| *p<0.05 between baseline and amiloride treatment phases; **p<0.001 between baseline and amiloride treatment phases; †p<0.05 between placebo and amiloride treatment phases. | ||||
| QTc, corrected QT interval. | ||||
| QT dispersion (ms) | 65.4 (29.2) | 65.7 (25.8) | 50.9 (26.1)**† | 14.8 (9.6) 95% CI 7.9 to 21.7, p=0.001 |
| QTc dispersion (ms) | 68.2 (29.0) | 68.3 (24.8) | 52.6 (25.3)**† | 15.7(10.0) 95% CI 8.6 to 22.9, p=0.001 |
| QTcmax (ms) | 442.6 (24.6) | 445.0 (26.6) | 435.2 (25.7)*† | 9.8 (9.1) 95% CI 3.3 to 16.2, p=0.008 |