Comparison of spironolactone versus amiloride in chronic heart failure
| Spironolactone | Amiloride | |
|---|---|---|
| Endothelial function | Improves4 | No effect |
| Vascular ACE | Improves4 | No effect |
| Collagen markers | Improves2 | No effect |
| Autonomic imbalance | Improves2,5 | No effect |
| QTcmax | Improves5 | Improves |
| Ventricular extrasystoles | Improves3 | Improves |