IC50 (mmol/l): concentration of angiotensin converting enzyme (ACE) inhibitor inhibiting 50% of matrix metalloproteinase (MMP) zymographic activity as a measure of the in vitro MMP inhibitory capacity of different ACE inhibitors
| MMP-2 | MMP-9 | |
|---|---|---|
| Values are mean (SD). | ||
| Captopril | 2.00 (0.06) | 1.65 (0.18) |
| Lisinopril | 5.40 (0.28) | 7.86 (0.43) |
| Ramipril | 2.10 (0.09) | 2.01 (0.30) |