Effect of BQ-123 infusion in patients with complete mixing
| Saturation aorta (%) | mPAP (mm Hg) | PVRI (dyne.s.cm−5) | PVRI/SVRI ratio | Qp (l/min/m2) | Qs (l/min/m2) | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Patient | 0 min | 60 min | 0 min | 60 min | 0 min7 | 60 min | 0 min | 60 min | 0 min | 60 min | 0 min | 60 min |
| **p<0.01 v baseline. | ||||||||||||
| mPAP, mean pulmonary artery pressure; PVRI, pulmonary vascular resistance index; Qp, pulmonary cardiac index; Qs, systemic cardiac index; SVRI, systemic vascular resistance index. | ||||||||||||
| 21 | 70 | 75 | 92 | 83 | 1824 | 1344 | 0.8 | 0.6 | 3.7 | 4.6 | 3.1 | 2.6 |
| 22 | 80 | 86 | 71 | 59 | 704 | 472 | 0.6 | 0.4 | 6.3 | 7.6 | 5.1 | 3.8 |
| 23 | 84 | 86 | 90 | 90 | 1864 | 1552 | 0.4 | 0.3 | 2.8 | 3.4 | 2.1 | 2.0 |
| 24 | 88 | 88 | 74 | 68 | 672 | 648 | 0.5 | 0.4 | 6.2 | 5.8 | 3.8 | 3.4 |
| 25 | 95 | 95 | 95 | 91 | 1888 | 1168 | 0.7 | 0.5 | 3.6 | 5.5 | 2.7 | 3.0 |
| 26 | 95 | 95 | 99 | 77 | 2512 | 1920 | 1.3 | 1.0 | 3.0 | 3.0 | 3.7 | 3.1 |
| Mean (SEM) | 85 (4) | 87 (3) | 87 (5) | 78 (5)** | 1577 (300) | 1184 (223)** | 0.7 (0.1) | 0.5 (0.1)** | 4.3 (0.6) | 5.0 (0.7) | 3.4 (0.4) | 3.0 (0.3) |