Feature | Dilated (n=22) | Control (n=22) |
---|---|---|
*p<0.01. Values are mean (SEM). | ||
†Septicaemia, cardiac arrhythmia, hepatic failure. | ||
LV, left ventricular. | ||
Men:women | 14:8 | 7:15 |
Mean age (years) (range) | 71.8 (44–96) | 68.6 (30–97) |
Cardiac medications (number of patients receiving treatment) | ||
β Blockers | 0 | 2 |
Diuretics | 7 | 5 |
Ca2+ channel blockers | 1 | 3 |
Antiarrhythmics | 1 | 2 |
Digoxin | 3 | 1 |
Cause of death | ||
Respiratory tract infection | 6 | 3 |
Chronic obstructive airways disease | 3 | 0 |
Pulmonary embolism | 3 | 3 |
Ruptured aortic aneurysm | 2 | 1 |
Cerebrovascular accident | 2 | 4 |
Road traffic accident | 2 | 2 |
Carcinoma | 0 | 3 |
Gastrointestinal disease | 3 | 2 |
Suicide | 1 | 1 |
Others† | 0 | 3 |
Heart weight (g) | ||
Whole heart mass | 426.2 (16.6)* | 351.6 (15.3) |
Whole ventricular mass | 328.5 (21.7) | 268.6 (13.1) |
Left ventricle | 239.3 (12.6)* | 183.8 (9.7) |
Right ventricle | 84.6 (4.2) | 70.3 (3.9) |
Valve circumferences (cm) | ||
Aortic valve | 8.08 (0.22) | 7.42 (0.17) |
Mitral valve | 12.12 (0.18)* | 9.78 (0.17) |
Ventricular thickness (cm) | ||
Left ventricle | 1.72 (0.05) | 1.55 (0.06) |
Interventricular septum 1 | 1.80 (0.05) | 1.62 (0.06) |
Interventricular septum 2 | 1.81 (0.05) | 1.60 (0.06) |
Right ventricle | 0.57 (0.03) | 0.50 (0.03) |
LV volume (cm3) | 83..5 (4.7)* | 51..2 (2.7) |
LV mass:LV volume (g/cm3) | 2.86* | 3.59 |
Collagen proportion (%) | ||
Left ventricle | 6.14 (0.20)* | 3.76 (0.12) |
Interventricular septum | 6.25 (0.22)* | 3.70 (0.10) |
Right ventricle | 4.53 (0.14)* | 3.60 (0.10) |