Effect of genotypes on coronary extent scores
| Non-parametric test | Analysis of variance | Multivariate analysis of variance | ||||||
|---|---|---|---|---|---|---|---|---|
| Polymorphism | Genotype | N | Mean rank | p Value | Mean score | p Value | Mean score* | p Value* |
| *Adjusted for age, body mass index, hypertension, and diabetes. | ||||||||
| †Differences between D/D, I/D, and I/I. | ||||||||
| ‡D/D + I/D versus I/I. | ||||||||
| ACE I/D | D/D | 343 | 592.59 | 0.024† | 0.98 | 0.061† | 0.98 | 0.072† |
| I/D | 587 | 595.06 | 0.006‡ | 1.00 | 0.019‡ | 0.99 | 0.024‡ | |
| I/I | 232 | 530.79 | 0.81 | 0.82 | ||||
| AGT T174M | T/T | 863 | 579.44 | NS | 0.98 | NS | 0.97 | NS |
| T/M | 264 | 584.46 | 0.98 | 0.98 | ||||
| M/M | 29 | 496.12 | 0.69 | 0.69 | ||||
| AGTR1 A+1166C | A/A | 559 | 563.04 | NS | 0.96 | NS | 0.96 | NS |
| A/C | 458 | 570.67 | 0.97 | 0.96 | ||||
| C/C | 113 | 556.69 | 0.93 | 0.93 | ||||
| AGTR2 +1291G>T | G (male) | 665 | 445.65 | NS | 0.97 | NS | 0.93 | NS |
| T (male) | 220 | 435.00 | 0.90 | 0.90 | ||||
| G/G (female) | 151 | 141.40 | NS | 1.07 | NS | 1.07 | NS | |
| G/T (female) | 112 | 139.29 | 1.00 | 1.01 | ||||
| T/T (female) | 14 | 110.79 | 0.64 | 0.73 | ||||
| AGTR2 +1297G>A | G (male) | 453 | 435.07 | NS | 0.91 | NS | 0.90 | NS |
| A (male) | 433 | 452.32 | 1.00 | 1.00 | ||||
| G/G (female) | 66 | 138.65 | NS | 1.03 | NS | 1.08 | NS | |
| G/A (female) | 137 | 139.27 | 1.05 | 1.04 | ||||
| A/A (female) | 71 | 133.01 | 0.97 | 0.99 | ||||