Table 2

Clinical characteristics of the studies included in the meta-analysis

Reference	Mean age (years)	Male (%)	CAD (%)	DM (%)	Isotope used	Test used	Positivity criterion	Preop revascularisation (%)	Op cancelled (%)	TP	FN	TN	FP
CAD, coronary artery disease; DM, diabetes mellitus; EF, ejection fraction; FN, false negative; FP, false positive; NA, not applicable; Op, operation; Preop, preoperative; RWMA, resting wall motion abnormality; TN, true negative; TP, true positive; -, missing values.
Ambulatory electrocardiography
Ouyang⁵	64	71	71	29	NA	Preop monitoring	ST depression >1 mm	0	0	2	0	9	13
Raby⁶	66	70	40	21	NA	Preop monitoring	ST depression >1 mm	0	0	3	1	143	29
Pasternack⁷	70	79	41	–	NA	Preop monitoring	ST depression >1 mm	0	0	9	0	73	118
Mangano⁸	69	100	51	25	NA	Preop monitoring	ST depression >1 mm/ST elevation >2 mm	0	0	1	5	109	25
Fleischer⁹	66	61	57	34	NA	Preop monitoring	ST depression >1 mm/ST elevation >2 mm	0	0	1	2	49	15
McPhail¹⁰	67	86	–	–	NA	Preop monitoring	ST depression >1 mm	0	0	5	4	62	29
Kirwin¹¹	73	55	66	47	NA	Preop monitoring	ST depression >1 mm	0	0	1	14	73	8
Fleischer¹²	69	50	72	43	NA	Preop monitoring	ST depression >1 mm/ST elevation >2 mm	0	0	2	2	64	18
Exercise electrocardiography
Cutler¹³	62	77	–	–	NA	Treadmill/arm ergometry	ST depression >1 mm	8	0	8	1	79	32
Gardine¹⁴	–	–	–	–	NA	Treadmill	ST depression >1 mm	0	0	1	0	10	6
von Knorring¹⁵	–	–	52	–	NA	Treadmill	ST depression >1 mm	0	0	2	1	78	24
Hanson¹⁶	62	73	20	–	NA	Arm ergometry	ST depression >1 mm	0	0	1	0	32	41
Leppo¹⁷	67	62	51	18	NA	Treadmill/arm ergometry	ST depression >1.5 mm	0	0	3	4	44	9
Kaaja¹⁸	–	67	29	22	NA	Bicycle	ST depression >1 mm	0	0	2	0	44	2
Urbinati¹⁹	62	74	15	46	NA	Bicycle	ST depression >1 mm	0	0	2	0	93	48
Radionuclide ventriculography
Fiser²⁰	61	100	25	–	Tc99m	NA	EF <30%	0	0	2	0	18	0
Pasternack²¹	70	96	34	–	Tc99m	NA	EF <35%	0	0	4	4	41	1
Mosley²²	–	90	63	–	Tc99m	NA	EF <35%	0	0	3	1	36	1
Pasternack²³	66	80	36	–	Tc99m	NA	EF <35%	1	0	6	8	84	1
Kazmers²⁴	68	–	42	7	Tc99m	NA	EF <35%	0	0	1	4	46	9
Franco²⁵	68	55	61	–	Tc99m	NA	EF <35%	0	0	3	12	58	12
McCann²⁶	68	87	49	–	Tc99m	NA	EF <35%	0	0	1	2	83	18
Fletcher²⁷	68	79	50	–	Tc99m	NA	EF <35%	0	0	3	0	62	7
Myocardial perfusion scintigraphy
Boucher²⁸	63	96	100	–	T201	Planar	Fixed or reversible perfusion defect	11	0	3	0	20	25
Cutler²⁹	65	69	34	–	T201	Planar	Fixed or reversible perfusion defect	5	8	9	0	62	30
Fletcher³⁰	64	72	27	–	T201	Planar	Fixed or reversible perfusion defect	7	0	2	0	57	3
Sachs³¹	60	83	30	–	T201	Planar	Reversible perfusion defect	0	0	2	0	32	12
Lane³²	65	65	63	100	T201	Planar	Fixed or reversible perfusion defect	0	0	9	0	20	72
Eagle³³	66	71	29	18	T201	Planar	Reversible perfusion defect	0	0	13	2	116	69
Younis³⁴	65	72	42	31	T201	Planar	Fixed or reversible perfusion defect	4	15	8	0	51	48
McEnroe³⁵	69	58	28	–	T201	Planar	Fixed or reversible perfusion defect	8	0	4	2	44	37
Strawn³⁶	66	–	62	15	T201	Planar	Reversible perfusion defect	13	9	1	3	18	31
Waters³⁷	–	–	100	–	T201	Planar	Fixed or reversible perfusion defect	4	4	3	0	11	12
Mangano³⁸	–	98	45	25	T201	Planar/SPECT	Fixed or reversible perfusion defect	0	0	2	1	19	38
Hendel³⁹	–	65	35	23	T201	Planar	Reversible perfusion defect	0	0	23	5	155	144
Madsen⁴⁰	65	65	22	–	T201	Planar	Fixed or reversible perfusion defect	0	0	5	0	20	40
McPhail¹⁰	67	86	–	–	Tc99m	Planar	Fixed or reversible perfusion defect	0	0	6	3	67	24
Bry⁴¹	66	69	30	34	T201	Planar	Fixed or reversible perfusion defect	4	0	17	0	97	114
Baron⁴²	63	–	36	9	T201	SPECT	Fixed or reversible perfusion defect	0	0	26	16	187	228
Ombrellaro⁴³	68	62	38	23	T201/Tc99m	Planar	Fixed or reversible perfusion defect	7	0	2	2	125	33
Erickson⁴⁵	67	88	26	15	T201	Planar	Fixed or reversible perfusion defect	3	0	6	1	55	80
Vanzetto⁴⁶	65	94	36	13	T201	SPECT	Fixed or reversible perfusion defect	0	0	11	1	50	72
Klonaris⁴⁷	67	87	36	32	T201	Planar	Fixed or reversible perfusion defect	0	0	7	1	43	116
Huang⁴⁸	68	89	12	27	T201	SPECT	Fixed or reversible perfusion defect	0	0	5	0	24	75
de Virgilio⁴⁹	65	96	26	33	T201	Planar	Fixed or reversible perfusion defect	4	0	2	0	27	30
de Virgilio⁵⁰	65	78	29	74	T201/Tc99m	SPECT	Fixed or reversible perfusion defect	0	0	3	1	35	41
Dipyridamole stress echocardiography
Tischler⁵¹	68	61	34	29	NA	NA	New or worsening RWMA during test	0	0	4	0	100	5
Pasquet⁵²	67	84	19	17	NA	NA	New or worsening RWMA during test	9	0	2	3	99	25
Rossi⁵³	66	80	39	76	NA	NA	New or worsening RWMA during test	0	0	4	3	74	22
Sicari⁵⁴	66	88	20	11	NA	NA	New or worsening RWMA during test	0	0	15	2	419	73
Dobutamine stress echocardiography
Lalka⁵⁵	64	78	30	18	NA	NA	New or worsening RWMA during test	0	0	8	1	21	30
Davila-Roman⁵⁶	67	73	63	19	NA	NA	New or worsening RWMA during test	14	0	2	0	68	8
Langan⁵⁷	69	84	31	10	NA	NA	New or worsening RWMA during test	5	6	3	0	31	40
Poldermans⁵⁸	68	89	31	12	NA	NA	New or worsening RWMA during test	0	0	5	0	96	30
Eichelberger⁵⁹	68	60	37	29	NA	NA	New or worsening RWMA during test	0	0	2	0	48	25
Poldermans⁶⁰	67	85	31	11	NA	NA	New or worsening RWMA during test	0	0	17	0	228	55
Shafritz⁶¹	66	64	33	17	NA	NA	New or worsening RWMA during test	0	0	1	0	30	11
Boersma⁶²	69	78	43	15	NA	NA	New or worsening RWMA during test	0	0	29	14	863	187