Table 1

Twenty most commonly reported drugs associated with torsades de pointes (TdP) between 1983 and 1999³

Drug	TdP (n)	Fatal (n)	Total (n)	TdP/total (%)
TdP (n), total number of adverse drug reaction reports which named TdP associated with this drug; Fatal (n): number of adverse drug reaction reports which named TdP with fatal outcome; Total (n): total number of adverse drug reaction reports for the drug.
Sotalol	130	1	2758	4.71
Cisapride	97	6	6489	1.49
Amiodarone	47	1	13725	0.34
Erythromycin	44	2	24776	0.18
Ibutilide	43	1	173	24.86
Terfenadine	41	1	10047	0.41
Quinidine	33	2	7353	0.45
Clarithromycin	33	0	17448	0.19
Haloperidol	21	6	15431	0.14
Fluoxetine	20	1	70929	0.03
Digoxin	19	0	18925	0.10
Procainamide	19	0	5867	0.32
Terodiline	19	0	2248	0.85
Fluconazole	17	0	5613	0.30
Disopyramide	16	1	3378	0.47
Bepridil	15	0	384	3.91
Furosemide	15	0	15119	0.10
Thioridazine	12	0	6565	0.18
Flecainide	11	2	3747	0.29
Loratidine	11	1	5452	0.20