Comparison of clinical characteristics and serum concentrations of sFas and sFas-L in patients with or without left ventricular remodelling
| Remodelling group | Non-remodelling group | p Value | |
|---|---|---|---|
| CK, creatine kinase concentration; IRCA, infarct related coronary artery; LAD, left anterior descending coronary artery; LCx, left circumflex coronary artery; LVEF, left ventricular ejection fraction; NS, not significant; PCWP, pulmonary capillary wedge pressure; RCA, right coronary artery. | |||
| n | 18 | 34 | NS |
| Male/female | 13/5 | 28/6 | NS |
| Age (years) | 62 (12) | 66 (10) | NS |
| Maximum CK (IU/l) | 3266 (2438) | 2694 (2213) | NS |
| PCWP (mm Hg) | 16.2 (7.8) | 14.4 (7.6) | NS |
| Cardiac index (l/min/m2) | 3.15 (0.87) | 2.90 (0.87) | NS |
| LVEF (%) | 49.2 (9.7) | 59.8 (10.1) | p<0.01 |
| IRCA | NS | ||
| LAD | 9 | 16 | |
| LCx | 2 | 5 | |
| RCA | 7 | 13 | |
| sFas (ng/ml) | |||
| Day 1 | 2.9 (1.2) | 2.8 (1.0) | NS |
| Day 7 | 2.3 (0.5) | 2.3 (0.7) | NS |
| Day 14 | 2.3 (0.7) | 2.2 (0.5) | NS |
| Day 21 | 2.1 (0.6) | 2.3 (0.6) | NS |
| sFas-L (pg/ml) | |||
| Day 1 | 71 (21) | 61 (21) | NS |
| Day 7 | 73 (23) | 63 (22) | NS |
| Day 14 | 87 (27) | 63 (20) | p<0.01 |
| Day 21 | 83 (25) | 62 (21) | p<0.01 |